EVIDENCE-BASED
The Science
Why bioavailability is everything.
Why cellular aging starts decades
before you notice it.
And why the form of a nutrient matters as much as the dose.
The supplement industry's dirty secret
BIO-AVAILABILITY
The label says 500mg. Your body absorbs 20mg. This is the reality of most supplement formulations — particularly for minerals, where the cheapest forms (oxides, carbonates) are used precisely because they are inexpensive, not because they work.
Bioavailability refers to the proportion of a nutrient that actually reaches systemic circulation and is available for use by the body. For magnesium oxide, this can be as low as 4%. For chelated forms like glycinate or malate, it routinely exceeds 50%. The difference is not marginal — it is the difference between a supplement that works and one that doesn't.
EverNutri formulates exclusively for bioavailability — using chelated minerals, liposomal delivery, phytosome complexes and stabilised active forms to ensure that the dose on the label is the dose that reaches your cells.
Why Therapeutic Dosing Matters
THERAPEUTIC DOSES
01
The ideal approach
A well-formulated supplement should have:
✔️ Ingredients supported by evidence
✔️ Ingredients provided at clinically relevant doses
✔️ High-quality raw materials
✔️ Appropriate delivery systems (such as liposomal technology where relevant)
✔️ Transparency about ingredient amounts
02
Benefits of therapeutic dosing
When a supplement is provided at an evidence-based therapeutic level:
✅ Greater likelihood of achieving the benefits observed in studies
✅ More predictable outcomes
✅ Better value for money
✅ Allows healthcare practitioners to use the supplement with confidence
✅ Supports long-term compliance because users are more likely to notice results
03
Why do some companies underdose?
There are a few reasons:
1. Cost
* Active ingredients are expensive.
* Lower doses improve profit margins.
2. Marketing
* A label can feature a trendy ingredient regardless of whether it’s included at an effective level.
3. Capsule space
* Capsules can only hold so much material.
* Some brands squeeze many ingredients into one formula but provide too little of each.
Why manufacturing conditions matter
MANUFACTURING
Supplement manufacturing is largely unregulated in the UK and EU. The majority of products are produced in standard food-grade facilities where contamination, inaccurate dosing and degraded active compounds are routine risks.
EverNutri manufactures in an ISO Class 8 cleanroom — the same environmental classification used in pharmaceutical manufacturing. Particle counts, microbial contamination, temperature and humidity are all continuously controlled and logged. Every batch is third-party tested for identity, purity and potency before release.
This level of manufacturing is more expensive. It is also the only way to guarantee that what is on the label is what is in the capsule — and that it will remain stable throughout the product's shelf life.
DELIVERY SYSTEMS
Hydrolyzation and Liposomal Delivery Systems: One ensures lower molecular weight for smaller peptides to be properly absorbed whilst true liposomal technology involves actually encapsulating the active ingredient within the phospholipid structure.
Hydrolization
The hydrolysation (more correctly, hydrolysis) process is what turns regular collagen into the collagen peptides found in supplements like EverCol. Collagen is typically sourced from bovine hides, fish skin, chicken cartilage, or other collagen-rich tissues. The raw material is cleaned and purified to isolate the collagen protein.
Hydrolysed collagen dissolves easily in hot or cold liquids, has very little taste or odour, is easier for the body to absorb compared with intact collagen and can achieve specific molecular weights (e.g., 2 kDa, 3 kDa, 5 kDa) depending on the manufacturing process. Does a lower molecular weight matter? Generally, smaller peptides are absorbed more efficiently through the intestinal wall. However, the quality of the raw material, manufacturing process, and clinical research behind the collagen are often more important than chasing the lowest molecular weight number.
SHOP THE PREMIUM RANGE →Liposomal Delivery
Liposomal delivery is one of the more interesting advances in supplementation because it’s designed to help protect nutrients from digestion and improve absorption. A liposome is a tiny microscopic sphere made from phospholipids—the same type of fat molecules that make up our cell membranes. The nutrient (such as vitamin C or hyaluronic acid) is encapsulated inside a protective phospholipid shell, allowing it to travel through the digestive system more effectively. Normally, when you swallow a supplement: 1. It enters the stomach. 2. Stomach acid and digestive enzymes begin breaking it down. 3. Only a proportion survives and is absorbed through the intestinal wall. 4. The rest is excreted. With liposomal delivery: 1. The nutrient is enclosed within the phospholipid membrane. 2. The liposome helps shield the ingredient from harsh digestive conditions. 3. The liposome can merge more readily with intestinal cell membranes because they’re made from similar phospholipids. 4. More of the nutrient may be delivered into circulation. Phospholipids are the ideal carrier because: * They’re biocompatible * They’re naturally found in human cell membranes * They help nutrients interact with cells more effectively
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